Non-clinical CRO
Lab Animal Center
AAALAC & Korean Excellent Animal Research Facility (KELAF) Accredited With internationally compliant animal management programs and cutting-edge facilities, we offer shared laboratory spaces and ensure reliable research outcomes.
Kolmar BioTech Lab Animal Center's Key Offerings
Under IACUC* supervision, the center offers cutting-edge animal housing and laboratory rental services, supported by a scientifically managed animal care program.
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01
1st AAALAC-Accredited Animal Facility Operated by Private Company in Korea
Facilitate IND filing to U.S. FDA or the European Medicines Agency.
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02
Korean Excellent Animal Research Facility(KELAF) Certified
Accredited for meeting the standards in personnel, facilities, operations, and programs required for the use and care of laboratory animals.
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03
In-house IACUC
Conducting internationally validated review process for animal research protocols and providing administrative support necessary for research.
*IACUC(Institutional Animal Care and Use Committee)
Main Services


Scientific laboratory animal care management under the
supervision of internal IACUC.
State-of-the-art animal room & laboratory rental services


Service that secures and offers experimental subjects
through natural mating or IVF of genetically modified mice.
= Colony Expansion Service.

- Disease Animal Model Creation and Dosing
- Dosing Methods
(intraperitoneal, oral, subcutaneous, intradermal, venous, intratracheal, spinal, intracerebral)
- Blood Collection
(Cardiac, Retro-Orbital plexu, jugular vein, abdominal aorta, posterior vein, tail vein, facial vein)
- Necropsy
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Location
kolmar BioCluster for New Drug Development, Floor B4 - B5
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Size
2,800m² , 10,000 Cages
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Species
Mouse, Rat
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Accreditations
Ministry of Food and Drug Safety,
Excellent Animal Research Facility
(No. 18, designated July 31, 2020)
AAALAC Accreditation
(Reacquired in June 2025)
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Key Facilities
BL2 SPF animal space
Behavioral observation room, Imaging room, Isolation room etc.
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Operating Hours
24/7 year-round
(Please inquire in advance for access outside of regular working hours)
Vivashare (Animal Research Laboratory)
We uphold the highest standards of laboratory animal care and management,
supported by TECNIPLAST's advanced equipment and Interceptor inspection, as
well as QM Diagnostics' state-of-the-art health monitoring services. As a partner
of the International Experimental Animal Association, QM Diagnostics' services are
exceptionally high in quality and reliability. Our unwavering objective is to ensure the
optimal health and well-being of the laboratory animals under our care.
- 10,000+ Cages
- 4 Change-Station available for free use in the housing room
- Shared laboratory available by reservation
- No. of entry: 2 person
- Standard housing allows up to 5 animals per cage
- For HFD studies, no more than 3 animals per cage are recommended
- Rats are recommended to be housed at 2 animals per cage
Equipment
DVC
GM500
+EM500
- Dedicated Space of 16.53m²
- 2 Racks with 160 cages
- 1 dedicated workbench
- No. of entry: 3 person
Basic Services Provided
- Service Details
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- PPE(Disposable): Dustproof suit, Hair cap, Mask, Gloves, Overshoes
- Disinfectant, Hand towel
- Experimental articles cabinet
- Ice, LN2
- O2 gas
- CO2 euthanasia chamber
- Medical waste disposal facilities
- Locker room, Shower room
- Rest area and Meeting space
- 365 days, 24/7 Free access anytime
- Online education, Service application
- Laboratory Animal Procurement Service
- Shared office space
Laboratory Animal Management Program
In partnership with QM Diagnostics, a 45-year leader in animal diagnostics, we assess infection status in mice through non-sacrificial methods.
- Breeding Room(Animal Housing Room)
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| Items |
Details |
| Air Handling Method |
Heating Ventilation Unit (HVU) |
| Temperature |
20 - 26 º C |
| Humidity |
30 - 70 % |
| Ventilation |
8 - 15 / 1 hour |
| Illumination |
12 h : 12 h (7:00 on, 19:00 off), 150 - 300 Lux |
- Cage
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| Item |
Details |
| Type/Manufacturer |
Individually Ventilated Cage (IVC) / Tecniplast |
| Model |
Mouse |
Rat |
| GM500 |
EM500 |
1145T |
1291H |
|
|
|
|
| Floor Area |
501 ㎠ |
512 ㎠ |
453 ㎠ |
800 ㎠ |
| Head* |
5 |
5 |
4 |
3 |
| Ventilation Rate |
75 Ventilation Rate |
75 Ventilation Rate |
75 Ventilation Rate |
75 Ventilation Rate |
*Mouse ≥ 25g , Rat ≥ 300g
- Breeding Management
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| Management Items |
Details |
| Feed |
R3+ (for maintenance) SAFE A30 (for breeding) |
| Feed Supply System |
Free ingestion |
| Water Supply |
Reverse Osmosis (RO) distilled water |
| Water Supply System |
Automatic water supply or bottle |
| Bedding |
ASPEN |
| Enrichment |
S-brick, M-brick, Cube, Igloo, Tunnel, Nestlets, Happi mat |
| Hygiene Management |
- Feed, bottle : Daily check, Replacement every once a week
Bedding :
Mouse - Replace once every 1 weeks
Rat - Replace once every 1 weeks
- Filter top, wire mesh : Replace once a month
|
| Sterilization Verification |
- Bowie Dick test
- BI (Dry & Wet type)
- CI
|
| Environmental Disinfection |
Disinfectant change every month (Bromcept, VirkonS, Chlorine bleach) |
Breeding Lab
A service with state-of-the-art equipment and
innovative management programs
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Mouse Strain recovery
(IVF-ET)
Applicable to laboratory animals infected with
pathogenic microorganisms, including transgenic
(TG) and knockout (KO) and KnockIn (KI) mice
Ensures SPF (Specific Pathogen-Free) con
ditions and reproducibility of experiments by
restoring breeding lines through embryo transfer
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Genotyping (PCR Analysis)
Maintains genetic consistency in laboratory
mice during colony maintenance
Minimizes experimental variability and en
sures consistent, reliable research outcomes
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Mouse Colony Maintenance and Breeding
Capable of large-scale production of genetically
engineered mice (GEM)
Enables cost-effective and consistent supply of
laboratory animal
Major Facilities and Equipment
Germ-Free
Microbiome Experiments
- Examine mechanisms of microorganisms or derived materials
- Breeding management know-how to maintain aseptic conditions and
integration of advanced equipment
IVIS Lumina 5X™ In vivo Imaging System
- Imaging of fluorescent or luminescent signals
labeled in cells or drugs
- Evaluation of anticancer candidates, Confirmation of
distribution of cell therapy agents
- Raji-Luc Xenograft Mode (IVIS Test Example)
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G1
G2
- Drug Distribution Study (IVIS Test Example)
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fluorescence
Insight Bone Density & Body Composition Analysis
- DEXA equipment with x-ray principles
- Used for experiments with osteoarthritis and
metabolic disorders(e.g. ob
- Metabolic Disorders and Musculoskeletal Diseases Study (DEXA Test Example)
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X-ray
Home-Cage Activity Analysis
- 24 hours of continuous activity data collection
- Evaluation of candidate substances for the treatment of degenerative brain diseases
- Initial safety screening of new drug candidates
Microbial / Environmental Monitoring
|
Test Item
|
Description
|
|
Cell Line Test
|
Heating Ventilation Unit (HVU)
|
Laboratory Animal Testing
|
20 - 26 ºC
|
| Health Monitoring |
Quarterly Sentinel animal testing
|
 |
|
Environmental Monitoring
|
Temperature and humidity, air quality, lighting, noise, drinking water, feed, airborne bacteria
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Health Monitoring
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Items
|
Frequency
|
Testing Method
|
Agency
|
|
Breeding Rooms
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Maximum
|
3 months
|
Sentinel animal testing exposed to Soiled bedding
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QM diagnostics
|
|
Other Housing Rooms
|
High+
|
3 months
|
Sentinel animal testing exposed to Soiled bedding
|
|
Environmental Monitoring
|
3 months
|
Illumination, temperature, humidity, noise, Microbial monitoring
|
Self-inspection
|
* Based on the section on standardizing health monitoring items for mice and rats in the Handbook of Health Monitoring for Laboratory Rodents, jointly published by the Korea Mouse Phenotyping Consortium (KMPC) and the Korean Society of Laboratory Animal Medicine (KCLAM).
Kolmar BioTech partners up with QM diagnostics, the world's
leading diagnostic company specialized in laboratory animals.
QM diagnostic is a 45-year-old European diagnostic
testing company
specializing in laboratory animals.
QM Accreditation
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ICLAS ANIMAL QUALITY NETWORK
It is registered with the International Council for Laboratory
Animal Science (ICLAS) Animal Quality Network.
(The Jaxon Lab and Charles River Lab are also registered.)
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ISO 17025 Accreditation
QM Diagnostics has been granted accreditation based on
ISO/IEC 17025:2017 with registration number L606.
ISO/IEC 17025:2017 specifies the general requirements
for the competence, impartiality, and consistent operation
of laboratories
Service
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Health monitoring
Particular rodents used for
biomedical research.
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Environmental monitoring
EAD Test(INTERCEPTOR®), Drinking water quality test
Carry-on Animal & Immunodeficiency Mouse
✓ Infection status can be checked without sacrificing the mouse (Excluding Pneumocysits carinii)
✓ Inspection is possible with small samples
Health Monitoring Items for Experimental Animals (KMPC & KCLAM Recommendations)
- Maximum Level
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| Virus |
Bacteria |
Parasites |
K-virus
Lactic dehydrogenase virus
Minute virus of mice
Mouse adenovirus (FL, K87)
Mouse cytomegalovirus
Mouse parvovirus
Mouse thymic virus
Pneumonia virus of mice
Polyoma virus
Reovirus 3
Rotavirus (EDIM)
Theiler’s murine encephalomyelitis virus
|
Bordetella bronchiseptica
Filobacterium rodentium (CAR bacillus)
Staphylococcus aureus
Streptobacillus moniliformis
|
Fungi
Dermatophytes
Encephalitozoon cuniculi
|
- High Level
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| Virus |
Bacteria |
Parasites |
Ectromelia virus
Hanta virus
Lymphocytic choriomeningitis virus
Mouse hepatitis virus
Murine norovirus
Sendai virus
|
CAP bacillus
Citrobacter rodentium
Clostridium piliforme
Corynebacterium bovis
Corynebacterium kutscheri
Helicobacter billis
Helicobacter hepaticus
Helicobacter typhlonius
Klebsiella pneumoniae
Klebsiella oxytoca
Mycoplasma pulmonis
Rodentibacter heylii
Rodentibacter pneumotropicus
Pseudomonas aeruginosa
Salmonella spp.
Streptococci β-hemolytic
Streptococcus pneumoniae |
Ectoparasites
Pinworms
Intestinal Protozoa
Fungi
Pneumocystis murina |
Animal Modeling Service
+more
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Disease Animal Model Creation and Dosing
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